Updated: September 28, 2023
Brayden was diagnosed with SMA-PME on August 10, 2018, shortly after his 3rd birthday. He received a follow-on diagnosis of Farber disease, an illness closely related to SMA-PME, at age 4.
Born: March 2015
At birth:
- Multiple ear infections
- Tubes before first birthday
First symptoms: 17 months
- Started walking, lots of falls
- Clumsy
- Suspected ear infections as cause
- Started physical therapy and speech therapy
- Second set of tubes replaced
Age 2 to 3:
- Still falling a lot, not catching himself
- Started on third set of tubes
- Adenoids removed
- Tremors began
- Thought to be caused by anesthesia from the surgery
- Tremors continued and worsened
- Hospitalized due to sudden inability to walk
- Doctors ran several tests
- First mention of SMA Type 2
- Tested negative for SMA Type 2
- Sought help from neurological specialist in Rochester, NY
- Muscle biopsy and genetic testing performed
- The confirmed diagnosis: SMA-PME
Our charity has seen that an absence of an accurate diagnosis for years seems a matter of course for both Farber and SMA-PME children.
Age 3 to 4:
- First noticed skin nodules
- A symptom of Farber disease
- Skin biopsy and more testing
- Searched solutions overseas
- Sent to France, connected with ASAP for Children charity and others
- Met a Canadian doctor in France who specializes in Farber disease
- Consulted this Farber specialist in Canada
- More specialists
Farber Disease. Another diagnosis, same ASAH1 gene mutation.
Age 4 to 5:
- Nodules in throat
- First scope of throat
- Fitted for first wheelchair
Age 5 to 6:
- First seizure, then another
- Started seizure medication
- First Electroencephalogram (EEG) conducted
- Surgery for trigger finger
Age 6-7:
- More seizures
- Respiratory infections: many
- Hospitalized
- Diagnoses included aspiration pneumonia
- Nasal gastric tube placed
- Feeding tube placed
Brayden’s seizures progress and intensify. Traditional medications do not improve this condition.
Age 7-8
- Put on Continuous Positive Airway Pressure (CPAP)
- Hospitalized for constant throwing up: medication formula change
- Could no longer walk on his own
- Wheelchair bound
- Needs help for every transfer
- Has hard time keeping his head up
- Seizures now a matter of course for Brayden
Little Brayden has been robbed of his childhood. He is so loved by his family.
- Brayden loves baseball
- A very special and courageous boy

